| Record Information |
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| Version | 2.0 |
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| Creation Date | 2009-06-19 21:58:31 UTC |
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| Update Date | 2014-12-24 20:23:31 UTC |
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| Accession Number | T3D1265 |
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| Identification |
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| Common Name | Stannane |
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| Class | Small Molecule |
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| Description | Stannane is a chemical compound of tin. Tin is a chemical element with the symbol Sn and atomic number 50. It is a natural component of the earth's crust and is obtained chiefly from the mineral cassiterite, where it occurs as tin dioxide. (2, 4) |
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| Compound Type | - Industrial/Workplace Toxin
- Inorganic Compound
- Synthetic Compound
- Tin Compound
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| Chemical Structure | |
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| Synonyms | | Synonym | | SnH4 | | Tetrahydridotin | | Tin tetrahydride | | [SnH4] |
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| Chemical Formula | H4Sn |
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| Average Molecular Mass | 122.740 g/mol |
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| Monoisotopic Mass | 123.933 g/mol |
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| CAS Registry Number | 2406-52-2 |
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| IUPAC Name | λ⁸-tin(4+) ion |
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| Traditional Name | λ⁸-tin(4+) ion |
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| SMILES | [SnH4] |
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| InChI Identifier | InChI=1S/Sn.4H |
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| InChI Key | InChIKey=KXCAEQNNTZANTK-UHFFFAOYSA-N |
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| Chemical Taxonomy |
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| Description | belongs to the class of inorganic compounds known as miscellaneous mixed metal/non-metals. These are inorganic compounds containing non-metal as well as metal atoms but not belonging to afore mentioned classes. |
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| Kingdom | Inorganic compounds |
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| Super Class | Mixed metal/non-metal compounds |
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| Class | Miscellaneous mixed metal/non-metals |
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| Sub Class | Not Available |
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| Direct Parent | Miscellaneous mixed metal/non-metals |
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| Alternative Parents | Not Available |
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| Substituents | - Miscellaneous mixed metal/non-metal
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| Molecular Framework | Not Available |
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| External Descriptors | Not Available |
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| Biological Properties |
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| Status | Detected and Not Quantified |
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| Origin | Exogenous |
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| Cellular Locations | |
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| Biofluid Locations | Not Available |
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| Tissue Locations | Not Available |
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| Pathways | Not Available |
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| Applications | Not Available |
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| Biological Roles | Not Available |
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| Chemical Roles | Not Available |
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| Physical Properties |
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| State | Gas |
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| Appearance | Not Available |
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| Experimental Properties | | Property | Value |
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| Melting Point | -146°C (127.15°K) | | Boiling Point | -52°C (221.15°K) | | Solubility | Not Available | | LogP | Not Available |
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| Predicted Properties | |
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| Spectra |
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| Spectra | Not Available |
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| Toxicity Profile |
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| Route of Exposure | Oral (3) ; inhalation (3) ; dermal (3) |
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| Mechanism of Toxicity | Inorganic and organic tin compounds are weak inhibitors of alcohol dehydrogenase. (1) |
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| Metabolism | Though tin metal is very poorly absorbed, tin compounds may be absorbed via oral, inhalation, or dermal routes, with organotin compounds being much more readily absorbed than inorganic tin compounds. Tin may enter the bloodstream and bind to hemoglobin, where it is distributed and accumulates mainly in the kidney, liver, lung, and bone. Tin and its metabolites are excreted mainly in the urine and feces. (3) |
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| Toxicity Values | Not Available |
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| Lethal Dose | Not Available |
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| Carcinogenicity (IARC Classification) | No indication of carcinogenicity to humans (not listed by IARC). |
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| Uses/Sources | Not Available |
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| Minimum Risk Level | Not Available |
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| Health Effects | Ingestion of large amounts of inorganic tin compounds can cause stomachache, anemia, and liver and kidney problems. (2, 3) |
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| Symptoms | Inorganic or organic tin compounds placed on the skin or in the eyes can produce skin and eye irritation. (3) |
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| Treatment | EYES: irrigate opened eyes for several minutes under running water. INGESTION: do not induce vomiting. Rinse mouth with water (never give anything by mouth to an unconscious person). Seek immediate medical advice. SKIN: should be treated immediately by rinsing the affected parts in cold running water for at least 15 minutes, followed by thorough washing with soap and water. If necessary, the person should shower and change contaminated clothing and shoes, and then must seek medical attention. INHALATION: supply fresh air. If required provide artificial respiration. |
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| Normal Concentrations |
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| Not Available |
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| Abnormal Concentrations |
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| Not Available |
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| External Links |
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| DrugBank ID | Not Available |
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| HMDB ID | Not Available |
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| PubChem Compound ID | 123161 |
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| ChEMBL ID | Not Available |
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| ChemSpider ID | 109776 |
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| KEGG ID | Not Available |
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| UniProt ID | Not Available |
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| OMIM ID | |
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| ChEBI ID | 30419 |
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| BioCyc ID | Not Available |
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| CTD ID | C031525 |
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| Stitch ID | Stannane |
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| PDB ID | Not Available |
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| ACToR ID | Not Available |
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| Wikipedia Link | Not Available |
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| References |
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| Synthesis Reference | Not Available |
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| MSDS | Not Available |
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| General References | - Bychkov PV, Shekhovtsova TN, Milaeva ER: Inhibition of horse liver alcohol dehydrogenase by methyltin compounds. Bioinorg Chem Appl. 2005:191-9. doi: 10.1155/BCA.2005.191. [18365099 ]
- Wikipedia. Tributyltin. Last Updated 31 May 2009. [Link]
- ATSDR - Agency for Toxic Substances and Disease Registry (2005). Toxicological profile for tin. U.S. Public Health Service in collaboration with U.S. Environmental Protection Agency (EPA). [Link]
- Wikipedia. Tin. Last Updated 28 May 2009. [Link]
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| Gene Regulation |
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| Up-Regulated Genes | Not Available |
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| Down-Regulated Genes | Not Available |
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