NameProtein phosphatase 1 regulatory subunit 11
Synonyms
  • HCG V
  • HCGV
  • Hemochromatosis candidate gene V protein
  • Protein phosphatase inhibitor 3
  • TCTE5
Gene NamePPP1R11
OrganismHuman
Amino acid sequence
>lcl|BSEQ0017692|Protein phosphatase 1 regulatory subunit 11
MAEAGAGLSETVTETTVTVTTEPENRSLTIKLRKRKPEKKVEWTSDTVDNEHMGRRSSKC
CCIYEKPRAFGESSTESDEEEEEGCGHTHCVRGHRKGRRRATLGPTPTTPPQPPDPSQPP
PGPMQH
Number of residues126
Molecular Weight13952.425
Theoretical pINot Available
GO Classification
Functions
  • protein serine/threonine phosphatase inhibitor activity
  • protein phosphatase 1 binding
Processes
  • negative regulation of phosphoprotein phosphatase activity
  • negative regulation of protein dephosphorylation
Components
  • cytoplasm
  • nucleus
  • protein phosphatase type 1 complex
General FunctionProtein serine/threonine phosphatase inhibitor activity
Specific FunctionInhibitor of protein phosphatase 1.
Pfam Domain Function
Transmembrane RegionsNot Available
GenBank Protein IDNot Available
UniProtKB IDO60927
UniProtKB Entry NamePP1RB_HUMAN
Cellular LocationNot Available
Gene sequence
>lcl|BSEQ0017693|Protein phosphatase 1 regulatory subunit 11 (PPP1R11)
ATGGCCGAGGCAGGGGCTGGGCTGAGCGAGACCGTCACTGAGACAACGGTTACCGTGACA
ACCGAGCCCGAGAACCGGAGCCTTACCATCAAACTTCGGAAACGGAAGCCAGAGAAAAAG
GTAGAATGGACAAGTGACACTGTGGACAATGAACACATGGGCCGCCGCTCATCCAAATGC
TGCTGTATTTATGAGAAACCTCGGGCCTTTGGCGAGAGCTCCACGGAAAGTGATGAGGAG
GAAGAAGAGGGCTGTGGTCATACACACTGTGTACGTGGCCACCGCAAAGGACGGCGTCGT
GCAACCCTAGGACCGACCCCCACCACCCCTCCCCAGCCTCCTGACCCTTCCCAGCCCCCT
CCAGGGCCAATGCAGCACTAA
GenBank Gene IDNot Available
GeneCard IDNot Available
GenAtlas IDNot Available
HGNC IDHGNC:9285
Chromosome Location6
LocusNot Available
References
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  2. Lepourcelet M, Andrieux N, Giffon T, Pichon L, Hampe A, Galibert F, Mosser J: Systematic sequencing of the human HLA-A/HLA-F region: establishment of a cosmid contig and identification of a new gene cluster within 37 kb of sequence. Genomics. 1996 Nov 1;37(3):316-26. 8938444
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  5. Zhang J, Zhang L, Zhao S, Lee EY: Identification and characterization of the human HCG V gene product as a novel inhibitor of protein phosphatase-1. Biochemistry. 1998 Nov 24;37(47):16728-34. 9843442
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