4773 Uracil mustard Uracil mustard is only found in individuals that have used or taken this drug. It is a nitrogen mustard derivative of uracil. It is a alkylating antineoplastic agent that is used in lymphatic malignancies, and causes mainly gastrointestinal and bone marrow damage. After activation, uracil mustard binds preferentially to the guanine and cytosine moieties of DNA, leading to cross-linking of DNA, thus inhibiting DNA synthesis and function. 66-75-1 6194 C8H11Cl2N3O2 White powder. 206°C 1070 mg/L After activation, it binds preferentially to the guanine and cytosine moieties of DNA, leading to cross-linking of DNA, thus inhibiting DNA synthesis and function. 2B, possibly carcinogenic to humans. (L135) Used for its antineoplastic properties. 2014-09-11T02:06:17Z 2014-12-24T20:26:56Z http://en.wikipedia.org/wiki/Uracil_mustard C11686 9884 DB00791 true OC1=NC=C(N(CCCl)CCCl)C(O)=N1 C8H11Cl2N3O2 InChI=1S/C8H11Cl2N3O2/c9-1-3-13(4-2-10)6-5-11-8(15)12-7(6)14/h5H,1-4H2,(H2,11,12,14,15) InChIKey=IDPUKCWIGUEADI-UHFFFAOYSA-N 252.098 251.022832025 Exogenous Solid 1.2 HMDB14929 CHEMBL1488 5959