4114 Retronecine Retronecine is a pyrrolizidine alkaloid found in a variety of plants in the genera Senecio and Crotalaria, and the family Boraginaceae. It is the most common central core for other pyrrolizidine alkaloids. 480-85-3 10198 C8H13NO2 White powder. 119°C Retronecine is classified as a pyrrolizidine alkaloid (PA). Unsaturated pyrrolizidine alkaloids are hepatotoxic, that is, damaging to the liver. PAs also cause hepatic veno-occlusive disease and liver cancer. PAs are tumorigenic. Disease associated with consumption of PAs is known as pyrrolizidine alkaloidosis. (Wikipedia) No indication of carcinogenicity to humans (not listed by IARC). Retronecine is a pyrrolizidine alkaloid found in a variety of plants in the genera Senecio and Crotalaria, and the family Boraginaceae. 2014-08-29T04:59:53Z 2014-12-24T20:26:37Z Retronecine C06177 true [H][C@@]1(O)CCN2CC=C(CO)[C@]12[H] C8H13NO2 InChI=1S/C8H13NO2/c10-5-6-1-3-9-4-2-7(11)8(6)9/h1,7-8,10-11H,2-5H2/t7-,8-/m1/s1 InChIKey=HJSJELVDQOXCHO-HTQZYQBOSA-N 155.1943 155.094628665 Exogenous Solid 9783