3659 Ochratoxin B Ochratoxin B is a metabolite of Aspergillus ochraceus Ochratoxin B belongs to the family of Ochratoxins and related substances. These are compounds containing the ochratoxin skeleton, which is structurally characterized by the presence of a 3-phenylpropanoic acid N-linked to a 8-hydroxy-3-methyl-1-oxo-3,4-dihydro-1H-2-benzopyran-7-carboxamide moiety[1]. (Reference: [1] http://www.inchem.org/documents/ehc/ehc/ehc105.htm). 4825-86-9 609663 C20H19NO6 Crystals from methanol. (A715) 221°C Oral, dermal, inhalation, and parenteral (contaminated drugs). (A3101) Ochratoxin B is thought to inhibit the accumulation of cartilage proteoglycans and general protein synthesis in a concentration-related manner. (A2872) Ochratoxin B is metabolized to 4-hydroxyochratoxin B. (A2871) No indication of carcinogenicity to humans (not listed by IARC). Human exposure occurs mainly through consumption of improperly stored food products, particularly contaminated grain and pork products, as well as coffee, wine grapes and dried grapes. (L1939) Ochratoxin exposure has been associated with acute tubular necrosis and Balkan endemic nephropathy. Ochratoxin A has been shown to be nephrotoxic; might delay sexual maturation. (A704) Might cause respiratory irritation. (A704) Care is symptomatic and supportive. (A704) 2009-11-13T22:46:58Z 2014-12-24T20:26:13Z true CC1CC2=C(C(=O)O1)C(O)=C(C=C2)C(O)=NC(CC1=CC=CC=C1)C(O)=O C20H19NO6 InChI=1/C20H19NO6/c1-11-9-13-7-8-14(17(22)16(13)20(26)27-11)18(23)21-15(19(24)25)10-12-5-3-2-4-6-12/h2-8,11,15,22H,9-10H2,1H3,(H,21,23)(H,24,25) InChIKey=DAEYIVCTQUFNTM-UHFFFAOYNA-N 369.368 369.121237345 Exogenous Solid HMDB29401 529965