3565 Methyl ethyl ketone peroxide Methyl ethyl ketone peroxide (MEKP) is an unstable organic peroxide used in the manufacture of acrylic resins, as a hardening agent for fiberglass-reinforced plastics, and as a curing agent for unsaturated polyester resins. It is commercially available as a 40% to 60% solution in dimethyl phthalate (DMP). MEKP is a severe skin irritant and can cause progressive corrosive damage or blindness. (L1788) (L1789) 1338-23-4 3672772 C8H18O6 210.110340 Colorless, oily liquid. (L1788) -8°C (265°K, 18°F) 109 °C (382°K, 228 °F) 1.15 g/cm³ 125-200 °F Oral (L1789) ; inhalation (L1789) ; dermal (L1789) MEPK toxicity could occur through lipid peroxidation. (L1789) LD50: 65 mg/kg (Intraperitoneal, Rat) (L1789) LD50: 484 mg/kg (Oral, Rat) (L1789) LC50: 200 mg/kg (Inhalation, Rat) (L1789) LC50: 170 mg/kg (Inhalation, Mouse) (L1789) No indication of carcinogenicity to humans (not listed by IARC). In the work environment, human exposure to MEKP occurs by inhalation of, and dermal exposure to, aerosolized MEKP during the spraying procedure used in some manufacturing processes, or by dermal exposure to the liquid substance. (L1789) MEKP is highly irritating and corrosive to skin and mucous membranes. A number of cases in which people accidentally or deliberately ingested MEKP solutions, occasionally with fatal results, have been reported. (L1789) Symptoms of acute MEKP poisoning by ingestion have included gastrointestinal bleeding, abdominal bums, necrosis, perforation of the stomach, stricture of the esophagus, severe metabolic acidosis, rapid hepatic failure, rhabdomyolysis, and respiratory insufficiency. Temporary cardiac arrest and toxic myocarditis have also been reported. (L1789) 2009-07-30T17:59:02Z 2014-12-24T20:26:07Z http://en.wikipedia.org/wiki/Methyl_ethyl_ketone_peroxide Methyl ethyl ketone peroxide 3949 true CCC(C)(OO)OOC(C)(CC)OO C8H18O6 InChI=1S/C8H18O6/c1-5-7(3,11-9)13-14-8(4,6-2)12-10/h9-10H,5-6H2,1-4H3 InChIKey=WFUGQJXVXHBTEM-UHFFFAOYSA-N 210.2249 210.110338308 Exogenous Liquid CHEMBL1562553