3138 T3D3096 D-Hyoscyamine Hyoscyamine is a plant toxin found in certain plants of the Solanaceae family, including henbane (Hyoscyamus niger), mandrake (Mandragora officinarum), jimsonweed (Datura stramonium), and deadly nightshade (Atropa belladonna). It is used as a drug to provide symptomatic relief to various gastrointestinal disorders including spasms, peptic ulcers, irritable bowel syndrome, pancreatitis, colic and cystitis. It has also been used to relieve some heart problems, control some of the symptoms of Parkinson's disease, as well as for control of respiratory secretions in palliative care.(L1255) 13269-35-7 637577 C17H23NO3 289.36942 White powder. Oral (ingestion) (L1817) ; dermal (L1817) Hyoscyamine is an anticholinergic, specifically an antimuscarinic, and works by blocking the action of acetylcholine at parasympathetic sites in smooth muscle, secretory glands, and the central nervous system. (L1255) No indication of carcinogenicity to humans (not listed by IARC). Hyoscyamine is a plant toxin found in certain plants of the Solanaceae family, including henbane (Hyoscyamus niger), mandrake (Mandragora officinarum), jimsonweed (Datura stramonium), and deadly nightshade (Atropa belladonna). It is used as a drug to provide symptomatic relief to various gastrointestinal disorders including spasms, peptic ulcers, irritable bowel syndrome, pancreatitis, colic and cystitis. It has also been used to relieve some heart problems, control some of the symptoms of Parkinson's disease, as well as for control of respiratory secretions in palliative care.(L1255) Hyoscyamine affects the central nervous system. (L1255) Side effects of hyoscyamine include dry mouth and throat, eye pain, blurred vision, restlessness, dizziness, arrythmia, flushing, and faintness. An overdose will cause headache, nausea, vomiting, and central nervous system symptoms including disorientation, hallucinations, euphoria, sexual arousal, short-term memory loss, and possible coma in extreme cases. (L1255) 2009-07-23T18:26:14Z 2014-12-24T20:25:58Z 48882 D-Hyoscyamine DB00424 true CN1C2CCC1CC(C2)OC(=O)C(CO)C1=CC=CC=C1 C17H23NO3 InChI=1/C17H23NO3/c1-18-13-7-8-14(18)10-15(9-13)21-17(20)16(11-19)12-5-3-2-4-6-12/h2-6,13-16,19H,7-11H2,1H3 InChIKey=RKUNBYITZUJHSG-UHFFFAOYNA-N 289.3694 289.167793607 Exogenous Solid <p>Jeffrey Kiel, H. Thomas, Emily Ware, Brady Ware, &#8220;Phenolic acid complexes of hyoscyamine and process for preparing the same.&#8221; U.S. Patent US20060128637, issued June 15, 2006.</p>