<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <id type="integer">2700</id>
  <title>T3D2658</title>
  <common-name>delta-Conotoxin (Conus striatus)</common-name>
  <description>Conotoxins are neurotoxic peptides from the venom of the marine cone snail (genus Conus). delta-Conotoxins inhibit the inactivation of voltage-dependent sodium channels. (L1107)</description>
  <cas></cas>
  <pubchem-id></pubchem-id>
  <chemical-formula nil="true"/>
  <weight>9216.754999999996</weight>
  <appearance>Clear solution.</appearance>
  <melting-point></melting-point>
  <boiling-point></boiling-point>
  <density nil="true"/>
  <solubility>&gt;10 mg/mL</solubility>
  <specific-gravity nil="true"/>
  <flash-point nil="true"/>
  <vapour-pressure nil="true"/>
  <route-of-exposure>Injection (sting/bite) (L1815)</route-of-exposure>
  <target nil="true"/>
  <mechanism-of-toxicity>delta-Conotoxins inhibit the inactivation of voltage-dependent sodium channels. (L1107)</mechanism-of-toxicity>
  <metabolism>Free toxin may be removed by opsonization via the reticuloendothelial system (primarily the liver and kidneys) or it may be degraded through cellular internalization via the lysosomes. Lysosomes are membrane-enclosed organelles that contain an array of digestive enzymes, including several proteases.</metabolism>
  <toxicity></toxicity>
  <lethaldose></lethaldose>
  <carcinogenicity>No indication of carcinogenicity to humans (not listed by IARC).</carcinogenicity>
  <use-source>Conotoxins are neurotoxic peptides from the venom of the marine cone snail (genus Conus). (L1107)</use-source>
  <min-risk-level></min-risk-level>
  <health-effects>Conotoxins are neurotoxic. (L1107)</health-effects>
  <symptoms>Cone snail stings can cause intense pain, swelling, numbness and tingling. Symptoms can start immediately or can be delayed in onset for days. Severe cases involve muscle paralysis, changes in vision and respiratory failure that can lead to death. (L1818)</symptoms>
  <treatment></treatment>
  <created-at type="dateTime">2009-07-07T21:54:31Z</created-at>
  <updated-at type="dateTime">2014-12-24T20:25:48Z</updated-at>
  <interacting-proteins nil="true"/>
  <wikipedia></wikipedia>
  <uniprot-id>Q9XZK5</uniprot-id>
  <kegg-compound-id></kegg-compound-id>
  <omim-id></omim-id>
  <chebi-id></chebi-id>
  <biocyc-id></biocyc-id>
  <ctd-id></ctd-id>
  <stitch-id>Conotoxin</stitch-id>
  <drugbank-id></drugbank-id>
  <pdb-id></pdb-id>
  <actor-id></actor-id>
  <organism nil="true"/>
  <export type="boolean">true</export>
  <metabolizing-proteins nil="true"/>
  <transporting-proteins nil="true"/>
  <moldb-smiles nil="true"/>
  <moldb-formula nil="true"/>
  <moldb-inchi nil="true"/>
  <moldb-inchikey nil="true"/>
  <moldb-average-mass type="decimal" nil="true"/>
  <moldb-mono-mass type="decimal" nil="true"/>
  <origin>Exogenous</origin>
  <state>Liquid</state>
  <logp></logp>
  <hmdb-id></hmdb-id>
  <chembl-id></chembl-id>
  <chemspider-id></chemspider-id>
  <structure-image-file-name>1g1p_asym_r_500.jpg</structure-image-file-name>
  <structure-image-content-type>image/jpeg</structure-image-content-type>
  <structure-image-file-size type="integer">31581</structure-image-file-size>
  <structure-image-updated-at type="dateTime">2014-10-14T18:13:59Z</structure-image-updated-at>
  <biodb-id>BSEQ0008516</biodb-id>
  <synthesis-reference></synthesis-reference>
  <structure-image-caption nil="true"/>
</compound>
