2689 Neoverrucotoxin Neoverrucotoxin is a peptide toxin found in the venom of the Reef stonefish (Synanceia verrucosa). They are the most venomous known fish in the world. (L1118, T170) 79669.8499999998 Clear solution. >10 mg/mL Injection (sting/bite) (L1815) Neoverrucotoxin has hemolytic activities. (T170) Free toxin may be removed by opsonization via the reticuloendothelial system (primarily the liver and kidneys) or it may be degraded through cellular internalization via the lysosomes. Lysosomes are membrane-enclosed organelles that contain an array of digestive enzymes, including several proteases. No indication of carcinogenicity to humans (not listed by IARC). Neoverrucotoxin is a peptide toxin found in the venom of the Reef stonefish (Synanceia verrucosa). (L1118, T170) Stonefish venom is hemolytic, neurotoxic, and cardiotoxin, and can be fatal if untreated. Surviving victims often suffer localized nerve damage occasionally leading to atrophy of adjoining muscle tissues.(L1118) Stonefish venom causes severe pain with possible shock, paralysis, and tissue death. (L1118) Treatment of stonefish venom immersion of the affected limb in hot water to denature the protein. Local anaesthetic may be administered for pain relief. There is also an available antivenom. (L1118) 2009-07-06T21:35:53Z 2014-12-24T20:25:48Z A0ZSK3 true Exogenous Liquid BSEQ0008512