2663 Streptolysin O (Streptococcus pyogenes) Streptolysin O is a hemolytic exotoxin produced by Streptococcus pyogenes. Streptolysin O is an oxygen-labile leukocidin. (L1783) 98072-47-0 63637.98999999986 Clear solution. >10 mg/mL Ingestion (L1816) ; inhalation (L1816) ; dermal (L1816) Streptolysin O binds to cholesterol on eukaryotic cell membranes, then is able to lyse them. (T170) Free toxin may be removed by opsonization via the reticuloendothelial system (primarily the liver and kidneys) or it may be degraded through cellular internalization via the lysosomes. Lysosomes are membrane-enclosed organelles that contain an array of digestive enzymes, including several proteases. LD50: 8 ug/mg (Intravenous, Mouse) (A2855) No indication of carcinogenicity to humans (not listed by IARC). Streptolysin O is a hemolytic exotoxin produced by Streptococcus pyogenes. (L1783) Streptolysin O is a hemolytic exotoxin. (L1783) Streptolysin O is a hemolytic exotoxin. (L1783) 2009-07-06T18:11:36Z 2014-12-24T20:25:47Z P0C0I3 Streptolysin O true Exogenous Liquid 4hsc_bio_r_500.jpg image/jpeg 50194 2014-10-14T18:13:44Z BSEQ0008493