2626 Taipoxin Taipoxin is a peptide toxin produced by the Australian taipan (Oxyuranus scutellatus scutellatus). It is an extremely potent neurotoxin that causes death from asphyxia following paralysis of the respiratory muscles. (L1106) 52019-39-3 13828.660000000007 Clear solution. >10 mg/mL Injection (sting/bite) (L1814) Taipoxin causes a gradual reduction to complete stop of evoked and spontaneous release of acetylcholine from motor nerve terminals. (L1106) Free toxin may be removed by opsonization via the reticuloendothelial system (primarily the liver and kidneys) or it may be degraded through cellular internalization via the lysosomes. Lysosomes are membrane-enclosed organelles that contain an array of digestive enzymes, including several proteases. LD50: 0.106 mg/kg (Subcutaneous, Mouse) (L1830) LD50: 0.013 mg/kg (Intravenous, Mouse) (L1830) LD50: 0.009 mg/kg (Intraperitoneal, Mouse) (L1830) No indication of carcinogenicity to humans (not listed by IARC). Taipoxin is a peptide toxin produced by the Australian taipan (Oxyuranus scutellatus scutellatus). (L1106) Taipoxin is an extremely potent neurotoxin that causes death from asphyxia following paralysis of the respiratory muscles. (L1106) Bites from snakes in the Elapidae family produce pain at the site of the bite, followed by drowsiness, weakness, excessive salivation, decreased blood pressure, difficulty breathing, and paralysis of the facial muscles, lips, tongue, and larynx. In addition, ptosis, blurring of vision, convulsions, and headache may occur. (T156) An antivenom exists for taipan venom. (L1044) 2009-07-05T17:25:22Z 2014-12-24T20:25:44Z http://en.wikipedia.org/wiki/Taipoxin P00614 Taipoxin 1LX1 true Exogenous Liquid 3vc0_bio_r_500.jpg image/jpeg 29234 2014-10-14T18:13:24Z BSEQ0008473