2623 Maurocalcin Maurocalcin is a peptide toxin produced by the Chactoid scorpion (Scorpio maurus palmatus). It modifies channel gating behaviour of the ryanodine receptor. (T170) 269745-22-4 3864.57 Clear solution. >10 mg/mL Injection (sting/bite) (L1813) Maurocalcin potently and reversibly modifies channel gating behaviour of the type 1 ryanodine receptor by inducing prominent subconductance behaviour. (T170) Free toxin may be removed by opsonization via the reticuloendothelial system (primarily the liver and kidneys) or it may be degraded through cellular internalization via the lysosomes. Lysosomes are membrane-enclosed organelles that contain an array of digestive enzymes, including several proteases. LD50: 9.37 mg/kg (Intravenous, Mouse) (T256) No indication of carcinogenicity to humans (not listed by IARC). Maurocalcin is a peptide toxin produced by the Chactoid scorpion (Scorpio maurus palmatus). (T170) Maurocalcin is neurotoxic. (T170) Scorpion stings cause tingling or burning at the site of the sting. In more severe cases, symptoms may include spasm in the throat, feeling of thick tongue, restlessness, muscular fibrillation, abdominal cramps, convulsions, incontinence, hypertension, hypotension, oliguria, cardiac arrhythmias, pulmonary edema, and respiratory failure. (T156) 2009-07-05T17:25:15Z 2014-12-24T20:25:44Z P60254 1C6W true Exogenous Liquid 1c6w_asym_r_500.jpg image/jpeg 32583 2014-10-14T18:13:22Z BSEQ0008471