<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <id type="integer">2590</id>
  <title>T3D2549</title>
  <common-name>Eledoisin (Eledone cirrhosa)</common-name>
  <description>Eledoisin is a tachykinin peptide found in the Curled octopus (Eledone cirrhosa). (L1109)</description>
  <cas>69-25-0</cas>
  <pubchem-id></pubchem-id>
  <chemical-formula nil="true"/>
  <weight>1206.41</weight>
  <appearance>Clear solution.</appearance>
  <melting-point></melting-point>
  <boiling-point></boiling-point>
  <density nil="true"/>
  <solubility>&gt;10 mg/mL</solubility>
  <specific-gravity nil="true"/>
  <flash-point nil="true"/>
  <vapour-pressure nil="true"/>
  <route-of-exposure>Injection (sting/bite) (L1815)</route-of-exposure>
  <target nil="true"/>
  <mechanism-of-toxicity>Eledoisin is a tachykinin peptide. Tachykinins excite neurons, evoke behavioural responses, are potent vasodilators and secretagogues, and contract (directly or indirectly) many smooth muscles. This is done by acting at the three tachykinin receptors. (T170, L1109, L1717)</mechanism-of-toxicity>
  <metabolism>Free toxin may be removed by opsonization via the reticuloendothelial system (primarily the liver and kidneys) or it may be degraded through cellular internalization via the lysosomes. Lysosomes are membrane-enclosed organelles that contain an array of digestive enzymes, including several proteases.</metabolism>
  <toxicity></toxicity>
  <lethaldose></lethaldose>
  <carcinogenicity>No indication of carcinogenicity to humans (not listed by IARC).</carcinogenicity>
  <use-source>Eledoisin is a tachykinin peptide found in the Curled octopus (Eledone cirrhosa). (L1109)</use-source>
  <min-risk-level></min-risk-level>
  <health-effects>Eledoisin is a tachykinin peptide. Tachykinins excite neurons, evoke behavioral responses, are potent vasodilators and contract (directly or indirectly) many smooth muscles. (L1717)</health-effects>
  <symptoms>Eledoisin is a tachykinin peptide. Tachykinins produce a  variety of symptoms that include vasodilation, hypertension, and stimulation of extravascular smooth muscle. (L1109)</symptoms>
  <treatment></treatment>
  <created-at type="dateTime">2009-07-03T22:19:20Z</created-at>
  <updated-at type="dateTime">2014-12-24T20:25:41Z</updated-at>
  <interacting-proteins nil="true"/>
  <wikipedia></wikipedia>
  <uniprot-id>P62933</uniprot-id>
  <kegg-compound-id></kegg-compound-id>
  <omim-id></omim-id>
  <chebi-id></chebi-id>
  <biocyc-id></biocyc-id>
  <ctd-id></ctd-id>
  <stitch-id>Eledoisin</stitch-id>
  <drugbank-id></drugbank-id>
  <pdb-id>1MXQ</pdb-id>
  <actor-id></actor-id>
  <organism nil="true"/>
  <export type="boolean">true</export>
  <metabolizing-proteins nil="true"/>
  <transporting-proteins nil="true"/>
  <moldb-smiles nil="true"/>
  <moldb-formula nil="true"/>
  <moldb-inchi nil="true"/>
  <moldb-inchikey nil="true"/>
  <moldb-average-mass type="decimal" nil="true"/>
  <moldb-mono-mass type="decimal" nil="true"/>
  <origin>Exogenous</origin>
  <state>Liquid</state>
  <logp></logp>
  <hmdb-id></hmdb-id>
  <chembl-id></chembl-id>
  <chemspider-id></chemspider-id>
  <structure-image-file-name>1mxq_asym_r_500.jpg</structure-image-file-name>
  <structure-image-content-type>image/jpeg</structure-image-content-type>
  <structure-image-file-size type="integer">14218</structure-image-file-size>
  <structure-image-updated-at type="dateTime">2014-10-14T18:13:18Z</structure-image-updated-at>
  <biodb-id>BSEQ0008467</biodb-id>
  <synthesis-reference></synthesis-reference>
  <structure-image-caption nil="true"/>
</compound>
