2579 beta-Bungarotoxin beta-Bungarotoxin is a peptide toxin produced by the Many-banded krait (Bungarus multicinctus). It is a neurotoxin and acts at the presynaptic terminal, where it causes release of acetylcholine and subsequent exhaustion of acetylcholine stores in the nerve terminal. (L1091) 12778-32-4 2432 9571.019999999997 Clear solution. >10 mg/mL Injection (sting/bite) (L1814) beta-Bungarotoxin acts at the presynaptic terminal, where it causes release of acetylcholine and subsequent exhaustion of acetylcholine stores in the nerve terminal by binding to proteins, most commonly actin. It can also block voltage-gated potassium channels. (T170, L1091, A317) Free toxin may be removed by opsonization via the reticuloendothelial system (primarily the liver and kidneys) or it may be degraded through cellular internalization via the lysosomes. Lysosomes are membrane-enclosed organelles that contain an array of digestive enzymes, including several proteases. LD50: 0.108 mg/kg (Subcutaneous, Mouse) (L1830) LD50: 0.113 mg/kg (Intravenous, Mouse) (L1830) LD50: 0.08 (Intraperitoneal, Mouse) (L1830) No indication of carcinogenicity to humans (not listed by IARC). beta-Bungarotoxin is a peptide toxin produced by the Many-banded krait (Bungarus multicinctus). (L1091) Many-banded krait bites can cause paralysis, respiratory failure and death. (L1089) Many-banded krait bites can cause paralysis, respiratory failure and death. (L1089) An antivenom exists for Many-banded krait venom. (L1044) 2009-07-03T22:19:16Z 2014-12-24T20:25:40Z P00987 beta-Bungarotoxin true CC1CC2OC3CC4OC(=O)C=C(C)C4OC3(C)CC2OC2CCC3(C)OC4(C)CC5OC6CC7OC8(C)C(O)CC(CC(=C)C=O)OC8CC7OC6C=CCC5(C)OC4CC3OC12 C50H70O14 InChI=1/C50H70O14/c1-25(24-51)14-28-17-37(52)50(8)41(54-28)19-33-34(61-50)18-32-29(55-33)10-9-12-46(4)42(58-32)23-49(7)40(62-46)21-39-47(5,64-49)13-11-30-44(60-39)26(2)15-31-36(56-30)22-48(6)38(57-31)20-35-45(63-48)27(3)16-43(53)59-35/h9-10,16,24,26,28-42,44-45,52H,1,11-15,17-23H2,2-8H3 InChIKey=LYTCVQQGCSNFJU-UHFFFAOYNA-N 895.0824 894.476556948 Exogenous Liquid 2338 1bun_bio_r_500.jpg image/jpeg 25039 2014-10-14T18:13:09Z BSEQ0008457