2566 Tamapin Tamapin is a peptide toxin produced by the Eastern Indian scorpion (Mesobuthus tamulus). It blocks small conductance calcium-dependent potassium channels. (L1064) 508220-81-3 3465.1000000000013 Clear solution. >10 mg/mL Injection (sting/bite) (L1813) Tamapin is a selective, potent, and reversible blocker of small conductance calcium-dependent potassium channels. It inhibits SK2 with the highest affinity, SK3 with an intermediate affinity and has the lowest affinity for SK1 channels. (L1064) Free toxin may be removed by opsonization via the reticuloendothelial system (primarily the liver and kidneys) or it may be degraded through cellular internalization via the lysosomes. Lysosomes are membrane-enclosed organelles that contain an array of digestive enzymes, including several proteases. No indication of carcinogenicity to humans (not listed by IARC). Tamapin is a peptide toxin produced by the Eastern Indian scorpion (Mesobuthus tamulus). (L1064) Tamapin is neurotoxic. (L1064) Scorpion stings cause tingling or burning at the site of the sting. In more severe cases, symptoms may include spasm in the throat, feeling of thick tongue, restlessness, muscular fibrillation, abdominal cramps, convulsions, incontinence, hypertension, hypotension, oliguria, cardiac arrhythmias, pulmonary edema, and respiratory failure. (T156) 2009-07-03T22:19:11Z 2014-12-24T20:25:39Z P59869 2CF1 true Exogenous Liquid 2ky3_asym_r_500.jpg image/jpeg 29293 2014-10-14T18:13:07Z BSEQ0008454