2552 kappa-Hefutoxin kappa-Hefutoxin is a peptide toxin produced by the Indian black scorpion (Heterometrus fulvipes). It blocks potassium channels. (L1048) 478621-50-0 2659.8650000000002 Clear solution. >10 mg/mL Injection (sting/bite) (L1813) kappa-Hefutoxin blocks voltage-gated potassium channels and also slows down their activation kinetics. (L1048) Free toxin may be removed by opsonization via the reticuloendothelial system (primarily the liver and kidneys) or it may be degraded through cellular internalization via the lysosomes. Lysosomes are membrane-enclosed organelles that contain an array of digestive enzymes, including several proteases. No indication of carcinogenicity to humans (not listed by IARC). kappa-Hefutoxin is a peptide toxin produced by the Indian black scorpion (Heterometrus fulvipes). (L1048) kappa-Hefutoxin is neurotoxic. (L1048) Scorpion stings cause tingling or burning at the site of the sting. In more severe cases, symptoms may include spasm in the throat, feeling of thick tongue, restlessness, muscular fibrillation, abdominal cramps, convulsions, incontinence, hypertension, hypotension, oliguria, cardiac arrhythmias, pulmonary edema, and respiratory failure. (T156) 2009-07-03T22:19:05Z 2014-12-24T20:25:38Z P82850 1HP9 true Exogenous Liquid 1hp9_asym_r_500.jpg image/jpeg 12881 2014-10-14T18:12:56Z BSEQ0008440