2550 Cobatoxin Cobatoxin is a peptide toxin produced by the Mexican scorpion (Centruroides noxius). It blocks calcium-activated and voltage-gated potassium channels. (L1045) 211688-17-4 7131.364999999995 Clear solution. >10 mg/mL Injection (sting/bite) (L1813) Cobatoxin blocks calcium-activated and voltage-gated potassium channels. (L1045) Free toxin may be removed by opsonization via the reticuloendothelial system (primarily the liver and kidneys) or it may be degraded through cellular internalization via the lysosomes. Lysosomes are membrane-enclosed organelles that contain an array of digestive enzymes, including several proteases. LD50: 25 ug/kg (Intracerebroventricular, Mouse) (T170) No indication of carcinogenicity to humans (not listed by IARC). Cobatoxin is a peptide toxin produced by the Mexican scorpion (Centruroides noxius). (L1045) Cobatoxin is neurotoxic and can cause paralysis. (L1045) Scorpion stings cause tingling or burning at the site of the sting. In more severe cases, symptoms may include spasm in the throat, feeling of thick tongue, restlessness, muscular fibrillation, abdominal cramps, convulsions, incontinence, hypertension, hypotension, oliguria, cardiac arrhythmias, pulmonary edema, and respiratory failure. (T156) 2009-07-03T22:19:04Z 2014-12-24T20:25:38Z O46028 1PJV true Exogenous Liquid 1pjv_asym_r_500.jpg image/jpeg 22386 2014-10-14T18:12:54Z BSEQ0008438