<?xml version="1.0" encoding="UTF-8"?>
<compound>
  <id type="integer">2530</id>
  <title>T3D2489</title>
  <common-name>Philanthotoxin</common-name>
  <description>Philanthotoxins are components of the venom of the Egyptian solitary wasp (Philanthus triangulum). They are four types of philantothoxins, alpha, beta, gamma, and delta. (L1016)</description>
  <cas>77108-00-0</cas>
  <pubchem-id>115201</pubchem-id>
  <chemical-formula>C23H41N5O3</chemical-formula>
  <weight>435.320940</weight>
  <appearance>White powder.</appearance>
  <melting-point></melting-point>
  <boiling-point nil="true"/>
  <density nil="true"/>
  <solubility></solubility>
  <specific-gravity nil="true"/>
  <flash-point nil="true"/>
  <vapour-pressure nil="true"/>
  <route-of-exposure>Injection (sting/bite) (L1811)</route-of-exposure>
  <target nil="true"/>
  <mechanism-of-toxicity>Philanthotoxins block glutamate receptors, especially the calcium permeable AMPA receptor and kainate receptor. (L1016)</mechanism-of-toxicity>
  <metabolism nil="true"/>
  <toxicity nil="true"/>
  <lethaldose nil="true"/>
  <carcinogenicity>No indication of carcinogenicity to humans (not listed by IARC).</carcinogenicity>
  <use-source>Philanthotoxins are components of the venom of the Egyptian solitary wasp (Philanthus triangulum). (L1016)</use-source>
  <min-risk-level nil="true"/>
  <health-effects>Philanthotoxins are neurotoxic. (L1016) </health-effects>
  <symptoms>Wasp and bee stings cause local pain and swelling. In some individuals an allergic reaction may result, which is usually anaphylactic and can be deadly. (L1825)</symptoms>
  <treatment nil="true"/>
  <created-at type="dateTime">2009-07-03T22:18:56Z</created-at>
  <updated-at type="dateTime">2014-12-24T20:25:35Z</updated-at>
  <interacting-proteins nil="true"/>
  <wikipedia nil="true"/>
  <uniprot-id></uniprot-id>
  <kegg-compound-id></kegg-compound-id>
  <omim-id></omim-id>
  <chebi-id></chebi-id>
  <biocyc-id></biocyc-id>
  <ctd-id>C034092</ctd-id>
  <stitch-id>Philanthotoxin</stitch-id>
  <drugbank-id nil="true"/>
  <pdb-id nil="true"/>
  <actor-id nil="true"/>
  <organism nil="true"/>
  <export type="boolean">true</export>
  <metabolizing-proteins nil="true"/>
  <transporting-proteins nil="true"/>
  <moldb-smiles>CCCC(=O)NC(CC1=CC=C(O)C=C1)C(=O)NCCCCNCCCNCCCN</moldb-smiles>
  <moldb-formula>C23H41N5O3</moldb-formula>
  <moldb-inchi>InChI=1S/C23H41N5O3/c1-2-7-22(30)28-21(18-19-8-10-20(29)11-9-19)23(31)27-17-4-3-13-25-15-6-16-26-14-5-12-24/h8-11,21,25-26,29H,2-7,12-18,24H2,1H3,(H,27,31)(H,28,30)</moldb-inchi>
  <moldb-inchikey>InChIKey=VRQNABCCOFCGJL-UHFFFAOYSA-N</moldb-inchikey>
  <moldb-average-mass type="decimal">435.6033</moldb-average-mass>
  <moldb-mono-mass type="decimal">435.320940203</moldb-mono-mass>
  <origin>Exogenous</origin>
  <state>Solid</state>
  <logp nil="true"/>
  <hmdb-id nil="true"/>
  <chembl-id nil="true"/>
  <chemspider-id nil="true"/>
  <structure-image-file-name nil="true"/>
  <structure-image-content-type nil="true"/>
  <structure-image-file-size type="integer" nil="true"/>
  <structure-image-updated-at type="dateTime" nil="true"/>
  <biodb-id nil="true"/>
  <synthesis-reference></synthesis-reference>
  <structure-image-caption nil="true"/>
</compound>
