813 Glufosinate Glufosinate or its ammonium salt DL-phosphinothricin is an active ingredient in several nonselective systemic herbicides such as Basta, Rely, Finale, Ignite, Challenge, and Liberty. It interferes with the glutamine biosynthetic pathway that binds to the glutamate site of the enzyme. Glufosinate-treated plants die due to a buildup of ammonia and a cessation of photosynthesis due to lack of glutamine. 51276-47-2 4794 C5H12NO4P 181.050390 White powder. 230°C Glufosinate irreversibly inhibits the enzyme glutamine synthetase, which decreases ammonia detoxification. Increased ammonia levels lead to impairment of photorespiration and photosynthesis in plants. (T10) No indication of carcinogenicity to humans (not listed by IARC). Seizures; muscle weakness (post-status epileptic myopathy); convulsions; and even death. (T10) Nausea, vomiting, and diarrhea that is followed in 24h by impaired respiration. (T10) 2009-06-05T18:18:33Z 2014-12-24T20:22:51Z C05042 52136 C003121 Glufosinate DB02663 true CP(O)(=O)CCC(N)C(O)=O C5H12NO4P InChI=1S/C5H12NO4P/c1-11(9,10)3-2-4(6)5(7)8/h4H,2-3,6H2,1H3,(H,7,8)(H,9,10) InChIKey=IAJOBQBIJHVGMQ-UHFFFAOYSA-N 181.1268 181.050394389 Exogenous Solid CHEMBL450298 4630