812 Acetochlor Acetochlor is an herbicide developed by Monsanto and Zeneca. It is a member of the class of herbicides known as chloroacetanilides (L920). 34256-82-1 1988 C14H20ClNO2 269.118260 Thick oily liquid, light amber to violet (A573). < 0°C 0.223 mg/mL at 25°C [SHIU,WY et al. (1990)] Inhalation (L919) ; oral (L919) ; dermal (L919) ; eye contact (L919) Its mode of action is elongase inhibition, and inhibition of geranylgeranyl pyrophosphate (GGPP) cyclisation enzymes (L920). LD50: 2953 mg/kg (Oral, Rat) (T95) LD50: 3667 mg/kg (Dermal, Rabbit) (T95) No indication of carcinogenicity to humans (not listed by IARC). It is used to control weeds in corn, and is particularly useful as a replacement for atrazine in the case of some important weeds. (L920). ARDS/acute lung injury, burns of the esophagus or gastrointestinal tract can result from acetochlor poisoning (T36). Acetochlor is mildly irritating to the skin and eyes. Exposure to metalaxyl often results in such nonspecific symptoms as headache, dizziness, weakness, and nausea. Acetochlor poisoning can produce an allergic hypersensitivity dermatitis or asthma with bronchospasm and wheezing with chronic exposure (T36). 2009-06-05T16:53:48Z 2014-12-24T20:22:51Z Acetochlore inhibits elongase, and geranylgeranyl pyrophosphate (GGPP) cyclisation enzymes (L920). C10925 2394 ALPHA-NAPHTHALENEACETAMIDE C043377 Acetochlor 6351 true CCOCN(C(=O)CCl)C1=C(C)C=CC=C1CC C14H20ClNO2 InChI=1S/C14H20ClNO2/c1-4-12-8-6-7-11(3)14(12)16(10-18-5-2)13(17)9-15/h6-8H,4-5,9-10H2,1-3H3 InChIKey=VTNQPKFIQCLBDU-UHFFFAOYSA-N 269.767 269.118256596 Exogenous Liquid CHEMBL1517425 1911