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Browsing toxins
| T3DB ID | Name CAS Number |
Formula Weight |
Structure | Type | Mechanism of Action |
|---|---|---|---|---|---|
| T3D3760 | Fumagillin 23110-15-8 |
C26H34O7 458.544 |
|
|
Fumagillin blocks blood vessel formation (angiogenesis) by inhibiting the enzyme methionine aminopeptidase 2. This prevents angiogenesis by arresting endothelial cells... more |
| T3D3762 | Janthitrem B 73561-90-7 |
C37H47NO5 585.7728 |
|
|
Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to... more |
| T3D3763 | Janthitrem C 73561-91-8 |
C37H47NO4 569.7734 |
|
|
Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to... more |
| T3D3764 | Janthitrem E 90986-50-8 |
C37H49NO6 603.7881 |
|
|
Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to... more |
| T3D3765 | Janthitrem F 90986-52-0 |
C39H51NO7 645.8247 |
|
|
Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to... more |
| T3D3766 | Janthitrem G 90986-51-9 |
C39H51NO6 629.8253 |
|
|
Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to... more |
| T3D3767 | Lolitrem B 81771-19-9 |
C42H55NO7 685.8886 |
|
|
The neurological effects of Lolitrem B are a result of its ability to inhibit large conductance calcium-activated potassium channels (BK channels). Lolitrem B binds to... more |
| T3D3768 | Luteoskyrin 21884-44-6 |
C30H22O12 574.4885 |
|
|
Luteoskyrin is hepatotoxic. It is thought that this is a result of its metabolic reduction to the semiquinone radical catalyzed by NADPH-dependent cytochrome reductase... more |
| T3D3769 | Kojic Acid 501-30-4 |
C6H6O4 142.1094 |
|
|
Kojic acid acts as a competitive and reversible inhibitor of animal and plant polyphenol oxidases (tyrosinases), xanthine oxidase, and D- and some L-amino acid oxidase... more |
| T3D3770 | Moniliformin 71376-34-6 |
C4H2O3 98.0569 |
|
|
Moniliformin reversibly inhibits the enzymes pyruvate dehydrogenase and alpha-ketoglutarate dehydrogenase by competing for the binding site of pyruvate. This interfere... more |
| T3D3771 | Restrictocin (Aspergillus restrictus) 1406-72-0 |
|
|
Restrictocin is a highly specific ribotoxin that inhibits protein synthesis by cleaving a single phosphodiester bond in the sarcin/ricin loop (SRL) of the 23S−28S rRNA... more | |
| T3D3773 | alpha-Sarcin (Aspergillus giganteus) 86243-64-3 |
|
|
alpha-Sarcin is a highly specific ribotoxin that inhibits protein synthesis by cleaving a single phosphodiester bond in the sarcin/ricin loop (SRL) of the 23S−28S rRNA... more | |
| T3D3774 | Secalonic Acid D 35287-69-5 |
C32H30O14 638.5722 |
|
|
Secalonic acid D (SAD) is though to induce cleft palate by causing the formation of smaller palatal shelves that fail to elevate and fuse. This inhibited palatal shelf... more |
| T3D3775 | Slaframine 20084-93-9 |
C10H18N2O2 198.2621 |
|
|
Slaframine is a parasympathomimetic compound and causes increased secretion by salivary glands, pancreas, and other exocrine and endocrine glands. This is due to its a... more |
| T3D3776 | Sporidesmin 1456-55-9 |
C18H20ClN3O6S2 473.951 |
|
|
Sporidesmin and its reduced (dithiol) form undergo cyclic reduction/autoxidation reactions with glutathione and other thiols, generating toxic superoxide radicals, hyd... more |
| T3D3777 | Paspalitrem A 63722-90-7 |
C32H39NO4 501.6564 |
|
|
Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to... more |
| T3D3778 | Paspalitrem B 63764-58-9 |
C32H39NO5 517.6558 |
|
|
Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to... more |
| T3D3779 | Paspalicine 11024-55-8 |
C27H31NO3 417.5399 |
|
|
Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to... more |
| T3D3780 | Paxilline 57186-25-1 |
C27H33NO4 435.5552 |
|
|
Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to... more |
| T3D3781 | Verrucosidin 88389-71-3 |
C24H32O6 416.5073 |
|
|
Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to... more |
| T3D3782 | Verruculogen 12771-72-1 |
C27H33N3O7 511.5668 |
|
|
Tremorgenic mycotoxins exert their toxic effects by interfering with neurotransmitter release, possibly by causing degeneration of nerve terminals. They are thought to... more |
| T3D3943 | 2,5-Pyridinedicarboxylic acid, dipropyl ester |
C13H17NO4 251.2784 |
|
Not Available | |
| T3D3787 | 6-Deisopropylatrazine |
C5H8ClN5 173.604 |
|
Not Available | |
| T3D3788 | Acephate |
C4H10NO3PS 183.166 |
|
Not Available | |
| T3D3789 | Acibenzolar-S-Methyl |
C8H6N2OS2 210.276 |
|
Not Available |