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Browsing toxins
| T3DB ID | Name CAS Number |
Formula Weight |
Structure | Type | Mechanism of Action |
|---|---|---|---|---|---|
| T3D0261 | 2,6-Dinitrotoluene 606-20-2 |
C7H6N2O4 182.1335 |
|
|
Dinitrotoluene may cause conversion of oxyhemoglobin to methemoglobin via oxidation of iron(II) to iron(III) by its metabolites. High levels of methemoglobin are remov... more |
| T3D0262 | Fluoride ion 016984-48-8 |
F 18.9984032 |
|
|
Fluoride ions are incorporated into bone by substituting for hydroxyl groups in the carbonate-apatite structure to produce hydroxyfluorapatite, thus altering the miner... more |
| T3D0264 | Methyl parathion 000298-00-0 |
C8H10NO5PS 263.207 |
|
|
The active metabolite of methyl parathion, methyl paraoxon, inactivates acetylcholinesterase by phosphorylating the active site of the enzyme, thus inhibiting its acti... more |
| T3D0265 | Pentaerythritol tetranitrate 78-11-5 |
C5H8N4O12 316.1366 |
|
|
Nitrate's toxicity is a result of it's conversion to nitrite once in the body. Nitrite causes the autocatalytic oxidation of oxyhemoglobin to hydrogen peroxide and met... more |
| T3D0271 | Styrene 100-42-5 |
C8H8 104.1491 |
|
|
Styrene 7,8-oxide, a metabolite of styrene, can form DNA adducts by binding to deoxyguanosine. It is also mutagenic and causes increased frequency of sister chromatid ... more |
| T3D0273 | 1,2,3,4,6,7,8-Heptachlorodibenzofuran 67562-39-4 |
C12HCl7O 409.307 |
|
|
Halogenated dibenzofurans (PCDFs and PBDFs) bind the aryl hydrocarbon receptor (AhR), which increases its ability to activate transcription in the XRE (xenobiotic reso... more |
| T3D0275 | Adamsite 578-94-9 |
C12H9AsClN 277.581 |
|
|
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co... more |
| T3D0276 | Arsenic trisulfide 1303-33-9 |
As4S6 492.076 |
|
|
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co... more |
| T3D0277 | Arsenic disulfide 1303-32-8 |
AsHS 107.995 |
|
|
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co... more |
| T3D0278 | Arsenic pentasulfide 1303-34-0 |
As2H10S5 320.248 |
|
|
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co... more |
| T3D0279 | Arsenic trichloride 7784-34-1 |
AsCl3 181.281 |
|
|
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co... more |
| T3D0282 | Arsenous acid 13464-58-9 |
AsHO2 107.9283 |
|
|
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co... more |
| T3D0283 | Arsenic acid 10102-53-1 |
AsH3O4 141.943 |
|
|
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co... more |
| T3D0285 | Ammonium arsenate 7784-44-3 |
AsH9N2O4 176.0041 |
|
|
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co... more |
| T3D0286 | Copper(II) arsenite 10290-12-7 |
|
|
Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec... more | |
| T3D0287 | Gallium arsenide 1303-00-0 |
AsGa 144.645 |
|
|
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co... more |
| T3D0288 | Copper arsenate 10103-61-4 |
|
|
Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec... more | |
| T3D0289 | Copper arsenate hydroxide 16102-92-4 |
AsCu2HO5 283.019 |
|
|
Excess copper is sequestered within hepatocyte lysosomes, where it is complexed with metallothionein. Copper hepatotoxicity is believed to occur when the lysosomes bec... more |
| T3D0290 | Potassium arsenite 10124-50-2 |
AsKO3 162.0181 |
|
|
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co... more |
| T3D0292 | Arsenic pentoxide 1303-28-2 |
As2O5 229.8402 |
|
|
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co... more |
| T3D0293 | Magnesium arsenate 10103-50-1 |
As2Mg3O8 350.753 |
|
|
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co... more |
| T3D0294 | Manganese arsenate 61136-68-3 |
As2Mn3O8 442.6525 |
|
|
Manganese is a cellular toxicant that can impair transport systems, enzyme activities, and receptor functions. It primarily targets the central nervous system, particu... more |
| T3D0296 | Lead arsenate 7784-40-9 |
AsHO4Pb 347.1 |
|
|
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co... more |
| T3D0297 | Potassium arsenate 7784-41-0 |
AsH2KO4 180.0334 |
|
|
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co... more |
| T3D0298 | Sodium arsenate 7631-89-2 |
AsH2NaO4 163.9248 |
|
|
Arsenic and its metabolites disrupt ATP production through several mechanisms. At the level of the citric acid cycle, arsenic inhibits pyruvate dehydrogenase and by co... more |