Showing toxin card for Polyvinyl acetate (T3D3469)
Legend: toxin field target field
| Version | 1.0 |
| Creation Date | 2009-07-30 17:58:33 |
| Update Date | 2010-01-11 23:28:27 |
| Accession Number | T3D3469 |
| Name | Polyvinyl acetate |
| Compound Type |
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| Description | Polyvinyl acetate is a rubbery synthetic polymer. It is a component of glue and is used mainly as an adhesive for porous materials, particularly for wood, paper, and cloth. While polyvinyl acetate itself is not considered hazardous, it usually contains trace amounts of its precursor, vinyl acetate, which is toxic. (S882, S883) |
| Synonyms |
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| Chemical IUPAC Name | Not Available |
| Chemical Formula | (C4H6O2)n |
| Chemical Structure | |
| CAS Registry Number | 9003-20-7 |
| InChI Identifier | Not Available |
| InChI Key | Not Available |
| PubChem Compound ID | 7904  |
| KEGG ID | C12282 |
| UniProt ID | Not Available |
| OMIM ID | Not Available |
| ChEBI ID | Not Available |
| BioCyc ID | Not Available |
| SuperToxic ID | Not Available |
| CTD ID | Not Available |
| Stitch ID | Polyvinyl acetate |
| DrugBank ID | Not Available |
| PDB ID | Not Available |
| ACToR ID | 16103 |
| Wikipedia Link | http://en.wikipedia.org/wiki/Polyvinyl_acetate |
| Monoisotopic Mass | 86.0897+ |
| MOL File | Not Available |
| PDB File | Not Available |
| SDF File | |
| SMILES | Not Available |
| Appearance | Not Available |
| Melting Point | Not Available |
| Solubility | Not Available |
| Predicted LogP | Not Available |
| Route of Exposure | Oral (S885) ; Inhalation (S885) ; Dermal (S885) |
| Mechanism of Action | Polyvinyl acetate usually contains trace amounts of its precursor, vinyl acetate. One of the metabolites of vinyl acetate, acetaldehyde, is a known animal carcinogen. Acetaldehyde can form adducts with DNA, causing damage such as cross-links. (S885, S891) |
| Metabolism | Vinyl acetate may be absorbed following ingestion, inhalation, or dermal exposure, and distributes throughout the body. It is rapidly hydrolyzed by esterases in the blood to acetate and the unstable intermediate, vinyl alcohol. Vinyl alcohol is then rapidly converted to acetaldehyde, which in turn is metabolized to acetate in the liver. This in turn is incorporated into the "2 carbon pool" of normal body metabolism and eventually forms carbon dioxide as the major breakdown product, which is expired. (S885) |
| Toxicity Values | Not Available |
| Lethal Dose | Not Available |
| Carcinogenicity (IARC Classification) | 3 (R264) |
| Uses/Sources | Polyvinyl acetate is a component of glue and is used mainly as an adhesive for porous materials, particularly for wood, paper, and cloth. (S882) |
| Minimum Risk Level | Not Available |
| Health Effects | Vinyl acetate may affect the immune system. It may also be a carcinogen. (S885) |
| Symptoms | Inhalation of vinyl acetate irritates the eyes, nose, and throat. Skin contact causes irritation and blisters. (S885) |
| Treatment | Not Available |
| General References |
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